LRRK2 inhibitor, GSK2578215A, Purity ≥98%

Synonym: 1285515-21-0; GSK-2578215A; GSK 2578215A; 5-(2-Fluoropyridin-4-yl)-2-phenylmethoxy-N-pyridin-3-ylbenzamide; LRRK2 inhibitor

MDL: MFCD22665702
CAS Number: 1285515-21-0
Compound CID: 68107965

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GSK2578215A, soluble in DMSO and insoluble in water and ethanol, is an effective autophagy signaling inhibitor, that has the ability to prevent the pathway of autophagy signaling by inhibiting LRRK2. The molecular weight of the compound is 399.42, and its molecular formula is C₂₄H₁₈FN₃O₂. It targets the LRRK2 (G2019S) and LRRK2 (WT).

Molecular Weight

399.42

Molecular Formula

C₂₄H₁₈FN₃O₂

Targets

LRRK2 (G2019S)

Form

Lyophilized powder

Purity

≥98%

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO (warmed): 73 mg/mL (182.76 mM); Water: insoluble; Ethanol: insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

GSK2578215A can be used for its effects on Parkinson’s disease and other conditions related to LRRK2 dysregulation.