LXR inhibitor, GW3965 HCl, Purity ≥98%

Synonym: 405911-17-3; GW-3965; GW3965 hydrochloride; 2-[3-[3-[[2-Chloro-3-(trifluoromethyl)phenyl]methyl-(2,2-diphenylethyl)amino]propoxy]phenyl]acetic acid; hydrochloride; LXR inhibitor

MDL: MFCD08276920
CAS Number: 405911-17-3
Compound CID: 16078973

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GW3965 HCl, soluble in DMSO and insoluble in water and ethanol, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting LXR. The molecular weight of the compound is 618.51, and its molecular formula is C₃₃H₃₁ClF₃NO₃·HCl. It targets the hLXRα (Cell-free assay), hLXRβ (Cell-free assay), and LXRα/SRC1LiSA (Cell-free assay).

Molecular Weight

618.51

Molecular Formula

C₃₃H₃₁ClF₃NO₃·HCl

Targets

hLXRα (Cell-free assay)

Form

Lyophilized powder

Purity

≥98%

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO (warmed): 16 mg/mL (25.86 mM); Water: insoluble; Ethanol: insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

GW3965 HCl can be studied extensively for its potential therapeutic applications in the treatment of dyslipidemia and atherosclerosis.