LY 344864 hydrochloride

Synonym: 1217756-94-9; LY344864; LY-344864

CAS Number: 1217756-94-9
Compound CID: 56972176

Product Size

1 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

MSDS

Properties

Description

LY 344864 hydrochloride inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets human 5-HT1A receptor, human 5-HT1B receptor, human 5-HT1D receptor, human 5-HT1E receptor, human 5-HT1F receptor, human 5-HT2A receptor, human 5-HT2B receptor, human 5-HT3A receptor, human 5-HT7 receptor, rat α1-adrenergic receptor, and rat α2-adrenergic receptor.

Molecular Weight

387.88

Molecular Formula

C₂₁H₂₃ClFN₃O

Targets

Human 5-HT1A receptor: 0.530 μM; Human 5-HT1B receptor: 0.549 μM; Human 5-HT1D receptor: 0.575 μM; Human 5-HT1E receptor: 1.415 μM; Human 5-HT1F receptor: 0.006 μM; Human 5-HT2A receptor: 3.499 μM; Human 5-HT2B receptor: 1.695 μM; Human 5-HT3A receptor: 3.935 mM; Human 5-HT7 receptor: 4.851 μM; Rat α1-adrenergic receptor: 5.06 μM; Rat α2-adrenergic receptor: 3.69 μM

Form

Lyophilized powder

Purity

Applications

LY 344864 hydrochloride can be used to research and develop therapeutic strategies for certain diseases that involve excessive activation of GPCR-G protein signaling pathways.