LY-411575

Synonym: 209984-57-6; (S)-2-((S)-2-(3, 5-Difluorophenyl)-2-hydroxyacetamido)-N-((S)-5-methyl-6-oxo-6, 7-dihydro-5H-dibenzo[b, d]azepin-7-yl)propanamide

CAS Number: 209984-57-6
PubChem CID: 10435235

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

MSDS

Properties

Description

LY-411575, soluble in DMSO and ethanol and insoluble in water, inhibits the activity of proteases, which are enzymes involved in the breakdown of proteins. It targets γ secretase (cell-based) (HEK293 cells expressing either APP or NδE), γ secretase (membrane-based) (HEK293 cells expressing either APP or NδE), and notch S3 cleavage (HEK293 cells expressing either APP or NδE).

Molecular Weight

479.48

Molecular Formula

C₂₆H₂₃F₂N₃O₄

Targets

γ Secretase (cell-based) (HEK293 cells expressing either APP or NδE): 0.082 nM; γ Secretase (membrane-based) (HEK293 cells expressing either APP or NδE): 0.078 nM; Notch S3 cleavage (HEK293 cells expressing either APP or NδE): 0.39 nM

Form

Lyophilized powder

Purity

Solubility

DMSO: 94 mg/mL (196.04 mM); Water: insoluble; Ethanol: 13 mg/mL (27.11 mM)

Applications

LY-411575 can be studied for its significant potential to act as an effective antiviral agent to prevent viral infections.

Publications

Publications (0)

Publications

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