Properties
Description
LY-411575, soluble in DMSO and ethanol and insoluble in water, inhibits the activity of proteases, which are enzymes involved in the breakdown of proteins. It targets γ secretase (cell-based) (HEK293 cells expressing either APP or NδE), γ secretase (membrane-based) (HEK293 cells expressing either APP or NδE), and notch S3 cleavage (HEK293 cells expressing either APP or NδE).
Molecular Formula
C26H23F2N3O4
Targets
γ Secretase (cell-based) (HEK293 cells expressing either APP or NδE): 0.082 nM; γ Secretase (membrane-based) (HEK293 cells expressing either APP or NδE): 0.078 nM; Notch S3 cleavage (HEK293 cells expressing either APP or NδE): 0.39 nM
Solubility
DMSO: 94 mg/mL (196.04 mM); Water: insoluble; Ethanol: 13 mg/mL (27.11 mM)
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
LY-411575 can be studied for its significant potential to act as an effective antiviral agent to prevent viral infections.
Storage
Store at -20℃, and keep desiccated.
