Properties
Description
LY2140023 (LY404039) inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets rat neurons expressing native mGlu2/3, recombinant human mGlu2, and recombinant human mGlu3.
Molecular Formula
C7H9NO6S
Targets
Rat neurons expressing native mGlu2/3: 88 nM (Ki); Recombinant human mGlu2: 149 nM (Ki); Recombinant human mGlu3: 92 nM (Ki)
Applications
LY2140023 (LY404039) can be used for its potential to enhance cognitive processes such as memory, attention, and executive function in these individuals.
