Properties
Description
LY2140023 (LY404039) inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets rat neurons expressing native mGlu2/3, recombinant human mGlu2, and recombinant human mGlu3.
Molecular Formula
C7H9NO6S
Targets
Rat neurons expressing native mGlu2/3: 88 nM (Ki); Recombinant human mGlu2: 149 nM (Ki); Recombinant human mGlu3: 92 nM (Ki)
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
LY2140023 (LY404039) can be used for its potential to enhance cognitive processes such as memory, attention, and executive function in these individuals.
Storage
Store at -20℃, and keep desiccated.