LY2811376

Synonym: 1194044-20-6; (S)-4-(2, 4-Difluoro-5-(pyrimidin-5-yl)phenyl)-4-methyl-5, 6-dihydro-4H-1, 3-thiazin-2-amine

CAS Number: 1194044-20-6
PubChem CID: 44251605

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

LY2811376, soluble in DMSO and ethanol and insoluble in water, interferes with or suppresses the transmission of signals between neurons in the nervous system. It targets Aβ, and BACE1.

Molecular Weight

320.4

Molecular Formula

C₁₅H₁₄F₂N₄S

Targets

Aβ: 300 nM; BACE1: 239 nM-249 nM

Form

Lyophilized powder

Purity

>98%

Solubility

DMSO: 16 mg/mL (49.94 mM); Water: insoluble; Ethanol: 63 mg/mL (196.65 mM)

Applications

LY2811376 can be used for its antitumor activity against various solid tumors, including breast cancer, lung cancer, colorectal cancer, and pancreatic cancer.