Cat. No.: X23-10-ZQ130
MDM2 inhibitor (4R,5S)-Nutlin carboxylic acid, Purity ≥98%
Synonym: 2306390-08-7; (4R,5S)-Nutlin carboxylic acid; 2-(4-((4R,5S)-4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl)-2-oxopiperazin-1-yl)acetic acid; 2-[4-[(4R,5S)-4,5-Bis(4-chlorophenyl)-2-(4-methoxy-2-propan-2-yloxyphenyl)-4,5-dihydroimidazole-1-carbonyl]-2-oxopiperazin-1-yl]acetic acid; MDM2 inhibitor
- CAS Number: 2306390-08-7
- Compound CID: 138911380
Product Size
1 mg; 2 mg; 5 mg; 10 mg; 25 mg
Properties
Description
(4R,5S)-Nutlin carboxylic acid prevents the degradation of p53 by inhibiting the MDM2-p53 interaction, leading to increased p53 levels and promoting apoptosis in p53-responsive cells.
Molecular Formula
C32H32Cl2N4O6
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
(4R,5S)-Nutlin carboxylic acid can be used to explore the stereo-specific inhibition of the p53-MDM2 interaction in cancer research.
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