Cat. No.: X23-10-ZQ145
MDM2 inhibitor MI-773, Purity ≥98%
Synonym: 1303607-07-9; MI-773; (2'R,3S,4'S,5'R)-6-Chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2,2-dimethylpropyl)-1,2-dihydro-N-(trans-4-hydroxycyclohexyl)-2-oxospiro[3H-indole-3,3'-pyrrolidine]-5'-carboxamide; MDM2 inhibitor
- CAS Number: 1303607-07-9
- Compound CID: 52938482
Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
MI-773 prevents the degradation of p53 by inhibiting the MDM2-p53 interaction, leading to increased p53 levels and promoting apoptosis in p53-responsive cells.
Molecular Formula
C29H34Cl2FN3O3
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
MI-773 can be used to study the effects of MDM2-p53 inhibition in cancer therapy by stabilizing and activating p53.
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