Cat. No.: X23-10-ZQ143
MDM2 inhibitor MX-69, Purity ≥98%
Synonym: 1005264-47-0; MX69; MX-69; 4-[8-[(3,4-Dimethylphenyl)sulfamoyl]-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]benzoic acid; 4-(8-(N-(3,4-Dimethylphenyl)sulfamoyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl)benzoic acid; 4-{8-[(3,4-Dimethylphenyl)sulfamoyl]-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl}benzoic acid; MDM2 inhibitor
- CAS Number: 1005264-47-0
- Compound CID: 4075607
Product Size
1 mg; 2 mg; 5 mg; 10 mg; 25 mg
Properties
Description
MX-69, soluble in DMSO and ethanol and insoluble in water, prevents the degradation of p53 by inhibiting the MDM2-p53 interaction, leading to increased p53 levels and promoting apoptosis in p53-responsive cells.
Molecular Formula
C27H26N2O4S
Solubility
DMSO: 92 mg/mL (193.86 mM); Water: Insoluble; Ethanol: 40 mg/mL (84.28 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
MX-69 can be studied for its role in disrupting the MDM2-p53 interaction, leading to enhanced p53 activity in cancer research.
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