MDM2 inhibitor NSC-207895, Purity ≥98%

Cat. No.: X23-10-ZQ132

MDM2 inhibitor NSC-207895, Purity ≥98%

Synonym: 58131-57-0; NSC 207895; NSC-207895; NSC207895; NSC 179940; 4-(4-Methyl-1-piperazinyl)-7-nitro-benzofurazan 3-oxide; MDM2 inhibitor

  • CAS Number: 58131-57-0
  • Compound CID: 42640
Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
MSDS
Properties
Description
NSC-207895, soluble in DMSO and insoluble in ethanol and water, prevents the degradation of p53 by inhibiting the MDM2-p53 interaction, leading to increased p53 levels and promoting apoptosis in p53-responsive cells. It targets p53 and MDMX.
Molecular Weight
279.25
Molecular Formula
C11H13N5O4
Targets
p53; MDMX: 2.5 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 0.39 mg/mL (1.39 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
NSC-207895 can be used to enhance p53 activity by inhibiting MDM2-p53 interactions in cancer cells.
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