MDM2 inhibitor Nutlin carboxylic acid, Purity ≥98%

Synonym: 2249750-27-2; Nutlin carboxylic acid; MDM2 ligand 1; rel-2-(4-((4S,5R)-4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl)-2-oxopiperazin-1-yl)acetic acid; MDM2 inhibitor

CAS Number: 2249750-27-2
Compound CID: 138576186

Product Size

1 mg; 2 mg; 5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Nutlin carboxylic acid prevents the degradation of p53 by inhibiting the MDM2-p53 interaction, leading to increased p53 levels and promoting apoptosis in p53-responsive cells.

Molecular Weight

639.53

Molecular Formula

C₃₂H₃₂Cl₂N₄O₆

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Nutlin carboxylic acid can be used to inhibit the interaction between p53 and MDM2, thereby activating the p53 pathway for potential cancer therapy research.

Storage

Store at -20ºC.