MDM2 inhibitor Nutlin carboxylic acid, Purity ≥98%

Synonym: 2249750-27-2; Nutlin carboxylic acid; MDM2 ligand 1; rel-2-(4-((4S,5R)-4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl)-2-oxopiperazin-1-yl)acetic acid; MDM2 inhibitor

CAS Number: 2249750-27-2
Compound CID: 138576186

Product Size

1 mg; 2 mg; 5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Nutlin carboxylic acid prevents the degradation of p53 by inhibiting the MDM2-p53 interaction, leading to increased p53 levels and promoting apoptosis in p53-responsive cells.

Molecular Weight

639.53

Molecular Formula

C₃₂H₃₂Cl₂N₄O₆

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Applications

Nutlin carboxylic acid can be used to inhibit the interaction between p53 and MDM2, thereby activating the p53 pathway for potential cancer therapy research.