MDM2 inhibitor NVP-CGM097, Purity ≥98%

Synonym: 1313363-54-0; NVP-CGM097; CGM097; CGM-097; CGM 097; NVP-CGM-097; 4UF6MSL0ZH; (S)-1-(4-Chlorophenyl)-7-isopropoxy-6-methoxy-2-(4-(methyl(((1R,4S)-4-(4-methyl-3-oxopiperazin-1-Yl)cyclohexyl)methyl)amino)phenyl)-1,2-dihydroisoquinolin-3(4H)-one; MDM2 inhibitor

MDL: MFCD28144684
CAS Number: 1313363-54-0
Compound CID: 53240420

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

NVP-CGM097, soluble in DMSO and ethanol and insoluble in water, prevents the degradation of p53 by inhibiting the MDM2-p53 interaction, leading to increased p53 levels and promoting apoptosis in p53-responsive cells.

Molecular Weight

659.26

Molecular Formula

C₃₈H₄₇ClN₄O₄

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 62 mg/mL (94.04 mM); Water: Insoluble; Ethanol: 62 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

NVP-CGM097 can be used to investigate the therapeutic effects of inhibiting the p53-MDM2 interaction on tumor growth.

Storage

Store at -20ºC.