Cat. No.: X23-10-ZQ122
MDM2 inhibitor RO8994, Purity ≥98%
Synonym: 1309684-94-3; RO8994; (2'R,3R,3'S,5'S)-N-(4-Carbamoyl-2-methoxyphenyl)-6-chloro-3'-(3-chloro-2-fluorophenyl)-5'-(2,2-dimethylpropyl)-2-oxospiro[1H-indole-3,4'-pyrrolidine]-2'-carboxamide; (2'S,3R,4'S,5'R)-N-(4-Carbamoyl-2-methoxyphenyl)-6-chloro-4'-(3-chloro-2-fluorophenyl)-2'-neopentyl-2-oxospiro[indoline-3,3'-pyrrolidine]-5'-carboxamide; MDM2 inhibitor
- CAS Number: 1309684-94-3
- Compound CID: 53238217
Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
RO8994 prevents the degradation of p53 by inhibiting the MDM2-p53 interaction, leading to increased p53 levels and promoting apoptosis in p53-responsive cells.
Molecular Formula
C31H31Cl2FN4O4
Identity
Confirmed by NMR/HPLC/MS.
Applications
RO8994 can be researched as an MDM2 inhibitor, preventing p53 degradation and enhancing its tumor-suppressor functions.
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