Cat. No.: X23-10-ZQ122
MDM2 inhibitor RO8994, Purity ≥98%
Synonym: 1309684-94-3; RO8994; (2'R,3R,3'S,5'S)-N-(4-Carbamoyl-2-methoxyphenyl)-6-chloro-3'-(3-chloro-2-fluorophenyl)-5'-(2,2-dimethylpropyl)-2-oxospiro[1H-indole-3,4'-pyrrolidine]-2'-carboxamide; (2'S,3R,4'S,5'R)-N-(4-Carbamoyl-2-methoxyphenyl)-6-chloro-4'-(3-chloro-2-fluorophenyl)-2'-neopentyl-2-oxospiro[indoline-3,3'-pyrrolidine]-5'-carboxamide; MDM2 inhibitor
- CAS Number: 1309684-94-3
- Compound CID: 53238217
Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
RO8994 prevents the degradation of p53 by inhibiting the MDM2-p53 interaction, leading to increased p53 levels and promoting apoptosis in p53-responsive cells.
Molecular Formula
C31H31Cl2FN4O4
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
RO8994 can be researched as an MDM2 inhibitor, preventing p53 degradation and enhancing its tumor-suppressor functions.
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