Properties
Description
YH239-EE, soluble in DMSO and ethanol and insoluble in water, prevents the degradation of p53 by inhibiting the MDM2-p53 interaction, leading to increased p53 levels and promoting apoptosis in p53-responsive cells. It targets p53/MDM2.
Solubility
DMSO: 85 mg/mL (168.51 mM); Water: Insoluble; Ethanol: 15 mg/mL (29.73 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
YH239-EE can be used to study the inhibition of MDM2-p53 interaction and its therapeutic potential in cancer treatment.