Properties
Description
AS703026, soluble in DMSO and insoluble in ethanol and water, prevents the phosphorylation and activation of ERK leading to reduced cell proliferation and induced apoptosis in cancerous cells.
Molecular Formula
C15H15FIN3O3
Solubility
DMSO: 78 mg/mL (180.89 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
AS703026 can be used to study the inhibition of MEK1/2 in signal transduction and cancer research.