MEK inhibitor AZD8330, Purity ≥98%

Synonym: AZD8330; 869357-68-6; AZD-8330; ARRY-424704; ARRY-704; AZD 8330; 2-((2-Fluoro-4-iodophenyl)amino)-N-(2-hydroxyethoxy)-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxamide; MEK inhibitor

CAS Number: 869357-68-6
Compound CID: 16666708

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

AZD8330, soluble in DMSO and ethanol and insoluble in water, prevents the phosphorylation and activation of ERK leading to reduced cell proliferation and induced apoptosis in cancerous cells. It targets ERK phosphorylation and MEK1/2.

Molecular Weight

461.2

Molecular Formula

C₁₆H₁₇FIN₃O₄

Targets

ERK phosphorylation: 0.4 nM; MEK1/2: 7 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 88 mg/mL (190.79 mM); Water: Insoluble; Ethanol: 88 mg/mL (190.79 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

AZD8330 can be used to study the inhibition of MEK1/2 in the MAPK signaling pathway for cancer research.

Storage

Store at -20ºC.