MEK inhibitor Cobimetinib, Purity ≥98%

Synonym: Cobimetinib (R-enantiomer); 934660-94-3; Cobimetinib R-enantiomer; Cobimetinib(GDC-0973; XL518); [3,4-Difluoro-2-(2-fluoro-4-iodoanilino)phenyl]-[3-hydroxy-3-[(2R)-piperidin-2-yl]azetidin-1-yl]methanone; MEK inhibitor

CAS Number: 934660-94-3
Compound CID: 16222097

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Cobimetinib prevents the phosphorylation and activation of ERK leading to reduced cell proliferation and induced apoptosis in cancerous cells.

Molecular Weight

531.31

Molecular Formula

C₂₁H₂₁F₃IN₃O₂

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Cobimetinib can be used to study the inhibition of MEK1/2 in oncological research and therapy.

Storage

Store at -20ºC.