Properties
Description
MEK162, soluble in DMSO and insoluble in ethanol and water, prevents the phosphorylation and activation of ERK leading to reduced cell proliferation and induced apoptosis in cancerous cells. It targets MEK.
Molecular Formula
C17H15BrF2N4O3
Solubility
DMSO: 86 mg/mL (194.91 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
MEK162 (Binimetinib) can be used to investigate the inhibition of MEK1/2 in the MAPK/ERK pathway for oncological research.
