MEK inhibitor PD184161, Purity ≥98%

Synonym: 212631-67-9; PD 184161; PD184161; PD-184161; 2-(2-Chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-bromobenzamide; 5-Bromo-2-(2-chloro-4-iodoanilino)-N-(cyclopropylmethoxy)-3,4-difluorobenzamide; MEK inhibitor

CAS Number: 212631-67-9
Compound CID: 9937619

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PD184161 prevents the phosphorylation and activation of ERK leading to reduced cell proliferation and induced apoptosis in cancerous cells.

Molecular Weight

557.55

Molecular Formula

C₁₇H₁₃BrClF₂IN₂O₂

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

PD184161 can be used to investigate MEK1/2 inhibition in the MAPK pathway for cancer research.

Storage

Store at -20ºC.