MEK inhibitor PD98059, Purity ≥98%

Synonym: 167869-21-8; PD98059; PD 98059; 2-(2-Amino-3-methoxyphenyl)-4H-chromen-4-one; 2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one; MEK inhibitor

MDL: MFCD00671789
CAS Number: 167869-21-8
Compound CID: 4713

Product Size

10 mg; 25 mg; 50 mg; 100 mg; 200 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PD98059, soluble in DMSO and insoluble in ethanol and water, prevents the phosphorylation and activation of ERK leading to reduced cell proliferation and induced apoptosis in cancerous cells. It targets MEK1.

Molecular Weight

267.3

Molecular Formula

C₁₆H₁₃NO₃

Targets

MEK1: 2 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 13 mg/mL (48.63 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

PD98059 can be used to examine the inhibition of MEK1, thereby blocking ERK activation in signal transduction studies.

Storage

Store at -20ºC.