MEK inhibitor Refametinib, Purity ≥98%

Synonym: Refametinib (R enantiomer); 923032-38-6; RDEA119 R enantiomer; Refametinib R enantiomer; N-[3,4-Difluoro-2-(2-fluoro-4-iodoanilino)-6-methoxyphenyl]-1-[(2R)-2,3-dihydroxypropyl]cyclopropane-1-sulfonamide; MEK inhibitor

CAS Number: 923032-38-6
Compound CID: 50912933

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Refametinib prevents the phosphorylation and activation of ERK leading to reduced cell proliferation and induced apoptosis in cancerous cells.

Molecular Weight

572.34

Molecular Formula

C₁₉H₂₀F₃IN₂O₅S

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Refametinib can be used to study the inhibition of MEK1/2 in cancer models and its potential therapeutic applications.

Storage

Store at -20ºC.