Methiothepin mesylate

Synonym: 74611-28-2; Ro-8-6837

CAS Number: 74611-28-2
Compound CID: 3039995

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Methiothepin mesylate inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets 5-HT1A receptor, 5-HT1B receptor, 5-HT1C receptor, 5-HT1D receptor, 5-HT2A receptor, 5-HT2B receptor, 5-HT2C receptor, 5-HT5A receptor, 5-HT5B receptor, 5-HT6 receptor, and 5-HT7 receptor.

Molecular Weight

452.65

Molecular Formula

C₂₁H₂₈N₂O₃S₃

Targets

5-HT1A receptor: 7.10 (pKd); 5-HT1B receptor: 7.28 (pKd); 5-HT1C receptor: 7.56 (pKd); 5-HT1D receptor: 6.99 (pKd); 5-HT2A receptor: 8.50 (pKi); 5-HT2B receptor: 8.68 (pKi); 5-HT2C receptor: 8.35 (pKi); 5-HT5A receptor: 7.0 (pKd); 5-HT5B receptor: 7.8 (pKd); 5-HT6 receptor: 8.74 (pKd); 5-HT7 receptor: 8.99 (pKd)

Form

Lyophilized powder

Purity

>98%

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Methiothepin mesylate can be used for its ability to modulate serotonin signaling in the brain.

Storage

Store at -20°C, and keep desiccated.