MGL-3196, Purity ≥98%

Synonym: 920509-32-6; MGL3196; MGL 3196; 2-[3,5-Dichloro-4-[(6-oxo-5-propan-2-yl-1H-pyridazin-3-yl)oxy]phenyl]-3,5-dioxo-1,2,4-triazine-6-carbonitrile

MDL: MFCD26142653
CAS Number: 920509-32-6
Compound CID: 15981237

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

MSDS

Properties

Description

MGL-3196, soluble in DMSO and insoluble in water and ethanol, is an orally small-molecule liver-directed thyroid hormone receptor agonist. The molecular weight of the compound is 435.22, and its molecular formula is C₁₇H₁₂Cl₂N₆O₄.

Molecular Weight

435.22

Molecular Formula

C₁₇H₁₂Cl₂N₆O₄

Form

Lyophilized powder

Purity

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO: 80 mg/mL (183.81 mM); Water: insoluble; Ethanol: insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

MGL-3196 can be studied extensively for its potential therapeutic applications in the treatment of metabolic diseases such as non-alcoholic fatty liver disease (NAFLD) and dyslipidemia by modulating lipid metabolism and insulin sensitivity.