Properties
Description
CK-636, soluble in DMSO and ethanol and insoluble in water, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting microtubule/tubulin. It targets the Bovine Arp2/3 complex, fission yeast Arp2/3 complex, and human Arp2/3 complex.
Molecular Weight
284.09833
Molecular Formula
C16H16N2OS
Targets
Bovine Arp2/3 complex: 32 μM; Fission yeast Arp2/3 complex: 24 μM; Human Arp2/3 complex: 4 μM
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 52 mg/mL (182.85 mM); Water: insoluble; Ethanol: 46 mg/mL
Stability
In its lyophilized form, the chemical remains stable for 36 months.
Quality Level
Research grade
Applications
CK-636 is a cytoskeletal signaling inhibitor that plays a key role in reducing the formation of lamellipodia, leading to a decrease in migration speed.
Storage
Store at -20ºC, and keep desiccated.
