Properties
Description
Combretastatin A4, soluble in DMSO and warmed ethanol and insoluble in water, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting microtubule/tubulin.
Molecular Formula
C18H20O5
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 58 mg/mL (183.34 mM); Water: insoluble; Ethanol (warmed): 31 mg/mL (97.99 mM); In vivo: 5% DMSO + 50% PEG 300 + ddH2O, 28 mg/mL
Stability
In its lyophilized form, the chemical remains stable for 36 months.
Quality Level
Research grade
Applications
Combretastatin A4 is a cytoskeletal signaling inhibitor that plays a key role in disrupting the blood supply to tumors.
Storage
Store at -20ºC, and keep desiccated.
