Microtubule/Tubulin inhibitor, Epothilone B, Purity ≥98%

Synonym: 152044-54-7; Patupilone; Epothilone-B; EPO906; (-)-Epothilone B; Epo B; (1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12,16-pentamethyl-3-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione

MDL: MFCD02101921
CAS Number: 152044-54-7
Compound CID: 448013

Product Size

2 mg; 5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Epothilone B, soluble in DMSO and ethanol and insoluble in water, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting microtubule/tubulin.

Molecular Weight

507.7

Molecular Formula

C₂₇H₄₁NO₆S

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 93 mg/mL (183.18 mM); Water: insoluble; Ethanol: 93 mg/mL (183.18 mM); In vivo: 30% PEG400 + 0.5% Tween80 + 5% propylene glycol, 4 mg/mL

Stability

In its lyophilized form, the chemical remains stable for 36 months.

Quality Level

Research grade

Applications

Epothilone B is a cytoskeletal signaling inhibitor that can be used for its antitumor activity.

Storage

Store at -20ºC, and keep desiccated.