Properties
Description
Ixabepilone, soluble in DMSO and ethanol and insoluble in water, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting microtubule/tubulin.
Molecular Formula
C27H42N2O5S
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 95 mg/mL (187.48 mM); Water: insoluble; Ethanol: 95 mg/mL (187.48 mM); In vivo: 2% DMSO + 30% PEG 300 + 2% Tween 80 + ddH2O, 6 mg/mL
Stability
In its lyophilized form, the chemical remains stable for 36 months.
Quality Level
Research grade
Applications
Ixabepilone is a cytoskeletal signaling inhibitor that plays a key role in stabilizing microtubules and disrupting mitosis in cancer cells.
Storage
Store at -20ºC, and keep desiccated.