Properties
Description
Monomethyl auristatin E, soluble in DMSO and ethanol and insoluble in water, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting microtubule/tubulin.
Molecular Formula
C39H67N5O7
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 93 mg/mL (129.52 mM); Water: insoluble; Ethanol: 93 mg/mL (129.52 mM)
Stability
In its lyophilized form, the chemical remains stable for 36 months.
Quality Level
Research grade
Applications
Monomethyl auristatin E is a cytoskeletal signaling inhibitor that can be used for its ability to deliver cytotoxic drugs directly to cancer cells, minimizing off-target effects and improving therapeutic efficacy.
Storage
Store at -20ºC, and keep desiccated.