Microtubule/Tubulin inhibitor, VcMMAE, Purity ≥98%

Synonym: 646502-53-6; Vedotin; MC-Val-Cit-PAB-MMAE; VcMMAE (GMP); [4-[[(2S)-5-(Carbamoylamino)-2-[[(2S)-2-[6-(2,5-dioxopyrrol-1-yl)hexanoylamino]-3-methylbutanoyl]amino]pentanoyl]amino]phenyl]methyl N-[(2S)-1-[[(2S)-1-[[(3R,4S,5S)-1-[(2S)-2-[(1R,2R)-3-[[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl]-methylamino]-3-methyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-N-methylcarbamate

MDL: MFCD25372036
CAS Number: 646502-53-6
Compound CID: 46944733

Product Size

1 mg; 2 mg; 5 mg; 10 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

VcMMAE, soluble in DMSO and ethanol and insoluble in water, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting microtubule/tubulin.

Molecular Weight

1316.63

Molecular Formula

C₆₈H₁₀₅N₁₁O₁₅

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 92 mg/mL (69.87 mM); Water: insoluble; Ethanol: 92 mg/mL (69.87 mM)

Stability

In its lyophilized form, the chemical remains stable for 36 months.

Quality Level

Research grade

Applications

VcMMAE is a cytoskeletal signaling inhibitor that can be used for its membrane permeability.

Storage

Store at -20ºC, and keep desiccated.