Properties
Description
Mirabegron, soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets β3-adrenoceptor.
Molecular Formula
C21H24N4O2S
Targets
β3-Adrenoceptor: 22.4 nM (EC50)
Solubility
DMSO: 70 mg/mL (176.53 mM); Water: insoluble; Ethanol: 7 mg/mL (17.65 mM)
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Mirabegron can be studied for its effect on reducing detrusor muscle contractions and increasing bladder storage capacity.
Storage
Store at -20°C, and keep desiccated.
