Properties
Description
Mirabegron, soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets β3-adrenoceptor.
Molecular Formula
C21H24N4O2S
Targets
β3-Adrenoceptor: 22.4 nM (EC50)
Solubility
DMSO: 70 mg/mL (176.53 mM); Water: insoluble; Ethanol: 7 mg/mL (17.65 mM)
Applications
Mirabegron can be studied for its effect on reducing detrusor muscle contractions and increasing bladder storage capacity.