ML347

Synonym: 1062368-49-3; ML 347; ML-347; 5-[6-(4-Methoxyphenyl)pyrazolo[1, 5-a]pyrimidin-3-yl]quinoline

CAS Number: 1062368-49-3
PubChem CID: 44577753

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

ML347, soluble in DMSO and insoluble in water and ethanol, blocks the function of Smad proteins in the TGF-β signaling pathway. It targets ALK1, ALK2, ALK3, and ALK6.

Molecular Weight

352.39

Molecular Formula

C₂₂H₁₆N₄O

Targets

ALK1: 46 nM; ALK2: 32 nM; ALK3: 10.8 μM; ALK6: 9.83 μM

Form

Lyophilized powder

Purity

>98%

Solubility

DMSO: 9 mg/mL (25.53 mM); Water: insoluble; Ethanol: insoluble

Applications

ML347 can be used as a selective agonist of the melanocortin 1 receptor (MC1R).