MNK inhibitor CGP 57380, Purity ≥98%

Synonym: CGP 57380; 522629-08-9; CGP-57380; MNK1 Inhibitor; N3-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine; 3-N-(4-fluorophenyl)-2H-pyrazolo[3,4-d]pyrimidine-3,4-diamine; MNK inhibitor

CAS Number: 522629-08-9
Compound CID: 11644425

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

CGP 57380, soluble in warmed DMSO and insoluble in water and ethanol, is a potent and selective MNK inhibitor. It targets MNK1.

Molecular Weight

244.23

Molecular Formula

C₁₁H₉FN₆

Targets

MNK1: 2.2 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 43 mg/mL (176.06 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

CGP 57380 can be utilized to study the inhibition of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1) in cancer research.

Storage

Store at -20ºC.

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