Properties
Description
TH588, soluble in warmed DMSO and warmed ethanol and insoluble in water, is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting MTH1. It targets the MTH1 (NUDT1).
Molecular Formula
C13H12Cl2N4
Targets
MTH1 (NUDT1): 5 nM
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO (warmed): 19 mg/mL (64.36 mM); Water: insoluble; Ethanol (warmed): 1 mg/mL (3.38 mM)
Stability
In its lyophilized form, the chemical remains stable for 36 months.
Quality Level
Research grade
Applications
TH588 is a DNA damage inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of Gaucher disease and other related lysosomal disorders.
Storage
Store at -20ºC, and keep desiccated.
