Properties
Description
AZD2014, soluble in DMSO and insoluble in ethanol and water, disrupts cell growth, proliferation, and survival by targeting a key component of cellular signaling pathways. It targets mTOR, P-Akt (S473), and pS6 (S235/236).
Molecular Formula
C25H30N6O3
Targets
mTOR: 2.8 nM; P-Akt (S473): 80 nM; pS6 (S235/236): 200 nM
Solubility
DMSO: 32 mg/mL (69.18 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
AZD2014 can be used to examine the dual inhibition of mTORC1 and mTORC2 pathways in cancer research.
