Properties
Description
CC-115, soluble in DMSO and insoluble in ethanol and water, disrupts cell growth, proliferation, and survival by targeting a key component of cellular signaling pathways. It targets DNA-PK, mTOR, mTORC1, mTORC2, and PI3Kα.
Molecular Formula
C16H16N8O
Targets
DNA-PK: 21 nM; mTOR: 13 nM; mTORC1; mTORC2; PI3Kα: 852 nM
Solubility
DMSO: 61 mg/mL (181.35 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
CC-115 can be used to research its effects as a dual PI3K/mTOR inhibitor in cancer and autoimmune diseases.
