mTOR inhibitor CC-223, Purity ≥98%

Synonym: 1228013-30-6; CC 223; CC223; mTOR inhibitor

CAS Number: 1228013-30-6
Compound CID: 58298316

Product Size

5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

CC-223, soluble in DMSO and ethanol and insoluble in water, disrupts cell growth, proliferation, and survival by targeting a key component of cellular signaling pathways. It targets cFMS, DNA-PK, FLT4, mTOR, and PI3Kα.

Molecular Weight

397.47

Molecular Formula

C₂₁H₂₇N₅O₃

Targets

cFMS: 28 nM; DNA-PK: 840 nM; FLT4: 651 nM; mTOR: 16 nM; PI3Kα: 4 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 70 mg/mL (176.11 mM); Water: Insoluble; Ethanol: 70 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

CC-223 can be used to explore its role as an mTORC1 and mTORC2 inhibitor in cancer and other proliferative diseases.