Properties
Description
Everolimus, soluble in DMSO and ethanol and insoluble in water, disrupts cell growth, proliferation, and survival by targeting a key component of cellular signaling pathways. It targets mTOR (FKBP12).
Molecular Formula
C53H83NO14
Targets
mTOR (FKBP12): 1.62.4 nM
Solubility
DMSO: 91 mg/mL (94.97 mM); Water: Insoluble; Ethanol: 6 mg/mL (6.26 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Everolimus can be used to research its mTOR inhibition properties for cancer and transplant rejection treatments.