Properties
Description
Everolimus, soluble in DMSO and ethanol and insoluble in water, disrupts cell growth, proliferation, and survival by targeting a key component of cellular signaling pathways. It targets mTOR (FKBP12).
Molecular Formula
C53H83NO14
Targets
mTOR (FKBP12): 1.62.4 nM
Solubility
DMSO: 91 mg/mL (94.97 mM); Water: Insoluble; Ethanol: 6 mg/mL (6.26 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Everolimus can be used to research its mTOR inhibition properties for cancer and transplant rejection treatments.