Properties
Description
FK-506, soluble in DMSO and ethanol and insoluble in water, disrupts cell growth, proliferation, and survival by targeting a key component of cellular signaling pathways. It targets FKBP12 (T cells).
Molecular Formula
C44H69NO12
Solubility
DMSO: 81 mg/mL (100.74 mM); Water: Insoluble; Ethanol: 71 mg/mL (88.31 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
FK-506 can be used to investigate its immunosuppressive properties through mTOR inhibition.
