mTOR inhibitor FK-506, Purity ≥98%

Synonym: 104987-11-3; FK506; Fujimycin; Prograf; Tacrolimus; mTOR inhibitor

CAS Number: 104987-11-3
Compound CID: 445643

Product Size

50 mg; 100 mg; 500 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

FK-506, soluble in DMSO and ethanol and insoluble in water, disrupts cell growth, proliferation, and survival by targeting a key component of cellular signaling pathways. It targets FKBP12 (T cells).

Molecular Weight

804

Molecular Formula

C₄₄H₆₉NO₁₂

Targets

FKBP12 (T cells)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 81 mg/mL (100.74 mM); Water: Insoluble; Ethanol: 71 mg/mL (88.31 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

FK-506 can be used to investigate its immunosuppressive properties through mTOR inhibition.