Properties
Description
GDC-0349, soluble in DMSO and ethanol and insoluble in water, disrupts cell growth, proliferation, and survival by targeting a key component of cellular signaling pathways. It targets mTOR and PI3Kα.
Molecular Formula
C24H32N6O3
Targets
mTOR: 3.8 nM (Ki); PI3Kα: 3 μM (Ki)
Solubility
DMSO: 79 mg/mL (174.56 mM); Water: Insoluble; Ethanol: 5 mg/mL (11.04 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
GDC-0349 can be used to analyze its selective mTOR inhibition properties in cancer research.
