Properties
Description
KU-0063794, soluble in DMSO and insoluble in ethanol and water, disrupts cell growth, proliferation, and survival by targeting a key component of cellular signaling pathways. It targets mTORC1 and mTORC2Cell-free assay).
Molecular Formula
C25H31N5O4
Targets
mTORC1: 10 nM; mTORC2Cell-free assay): 10 nM
Solubility
DMSO: 16 mg/mL (34.36 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
KU-0063794 can be used to research its selective inhibition of mTORC1 and mTORC2 in various disease models.