Properties
Description
PQR620, soluble in DMSO, water and ethanol, disrupts cell growth, proliferation, and survival by targeting a key component of cellular signaling pathways. It targets mTORC1 and mTORC2.
Molecular Formula
C21H25F2N7O2
Solubility
DMSO: 19 mg/mL (42.65 mM); Water: <1 mg/mL; Ethanol: 2 mg/mL (4.48 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
PQR620 is employed to investigate brain-penetrant mTORC1/mTORC2 inhibition in the context of neurological diseases.