mTOR inhibitor Torin 2, Purity ≥98%

Synonym: 1223001-51-1; Torin2; mTOR inhibitor

CAS Number: 1223001-51-1
Compound CID: 51358113

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

MSDS

Properties

Description

Torin 2, soluble in DMSO and insoluble in ethanol and water, disrupts cell growth, proliferation, and survival by targeting a key component of cellular signaling pathways. It targets ATM (PC3 cells), ATR (PC3 cells), DNA-PK (PC3 cells), and mTOR.

Molecular Weight

432.4

Molecular Formula

C₂₄H₁₅F₃N₄O

Targets

ATM (PC3 cells): 28 nM (EC₅₀); ATR (PC3 cells): 35 nM (EC₅₀); DNA-PK (PC3 cells): 118 nM (EC₅₀); mTOR: 0.25 nM (EC₅₀)

Form

Lyophilized powder

Purity

Solubility

DMSO: 18 mg/mL (41.63 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

Torin 2 is used to research selective inhibition of mTORC1 and mTORC2 in various cellular processes.