mTOR inhibitor WYE-354, Purity ≥98%

Synonym: 1062169-56-5; WYE354; mTOR inhibitor

CAS Number: 1062169-56-5
Compound CID: 44219749

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

WYE-354, soluble in DMSO and insoluble in ethanol and water, disrupts cell growth, proliferation, and survival by targeting a key component of cellular signaling pathways. It targets PI3Kα, PI3Kγ, Abl1, AuroraB, CDK1/CyclinB, CDK2/CyclinA, Chk1, ERK2, Fyn, GCK, and Hck.

Molecular Weight

495.5

Molecular Formula

C₂₄H₂₉N₇O₅

Targets

PI3Kα: 1.89 μM; PI3Kγ: 7.37 μM; Abl1: >50 μM; AuroraB: >50 μM; CDK1/CyclinB: >50 μM; CDK2/CyclinA: >50 μM; Chk1: >50 μM; ERK2: >50 μM; Fyn: >50 μM; GCK: >50 μM; Hck: >50 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 95 mg/mL (191.71 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

WYE-354 is used to investigate its role as an mTOR inhibitor, helping scientists understand mTOR-dependent cellular processes and potential cancer therapies.

Storage

Store at -20ºC.