Properties
Description
Zotarolimus, soluble in DMSO and ethanol and insoluble in water, disrupts cell growth, proliferation, and survival by targeting a key component of cellular signaling pathways. It targets FKBP-12.
Molecular Formula
C52H79N5O12
Solubility
DMSO: 89 mg/mL (92.11 mM); Water: Insoluble; Ethanol: 89 mg/mL (92.11 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Zotarolimus is utilized in research to assess its efficacy as an mTOR inhibitor, especially in anti-proliferative drug-eluting stent technology for preventing coronary artery restenosis.