Overview

Combining cutting-edge nanotechnology and biochemistry, CD BioGlyco has a professional GlycoNano™ Platform to help clients deliver high-performance Glyconanoparticle Development programs. Quantum dots (QDs), also known as semiconductor nanocrystal. It is a nanoparticle composed of elements of group II-VI (e.g., CdSe, CdTe, CdS, ZnSe, etc.) or group III-V (e.g., InP, mAs, etc.).

CD BioGlyco provides a wide range of QD Glyconanoparticle Production services such as N-acetyllactosamine-QD nanoparticle production to meet the research needs of our clients in different fields. N-acetyl lactamine is a biocompatible modifier that significantly improves the stability and biocompatibility of QDs, enabling them to show great potential for applications in bioimaging, molecular diagnostics, and drug delivery.

Customize Your Favorite N-Acetyllactosamine-QD Nanoparticle

Our company has a rigorous synthesis and analysis process to ensure the quality of our products. Whether you want to customize the shape, size, or biological properties, our highly trained research team provides you with the most satisfactory synthesis solution.

Synthesis of Mono and Bivalent N-acetyl lactosamine

• We offer efficient synthesis of N-acetyl lactosamine by azidoiodo-glycosylation reaction. Our researchers use 2-iodolactoyl azide as a donor to prepare ligands containing N-acetyl lactosamine.

Synthesis of QDs

• Our researchers have many years of operational experience in the synthesis of QDs. QDs need to be made under harsh reaction conditions, such as high temperature, no oxygen, and no water.

Synthesis of N-Acetyllactosamine-QD Nanoparticle

• To couple carbohydrates to quantum dot surfaces, we utilize a two-phase reaction system to prepare N-acetyllactosamine-QD nanoparticles. Moreover, our lab offers direct synthesis and multi-step synthesis.

Determination of the N-Acetyllactosamine-QD Nanoparticle

• We provide quantitative service of the number of sugar molecules on the surface of QDs by nuclear magnetic resonance (NMR). Based on the NMR data, we provide our clients with detailed information on the number of sugar ligands on the QDs, the size of the sugars and QDs, and the formula of the sugar QDs. Moreover, we provide transmission electron microscope (TEM) analysis and colorimetric analysis services.
• Our lab provides professional affinity analysis, fluorescent properties analysis, and surface plasmon resonance analysis services.

Workflow

Our service process includes demand communication, program development, synthesis and preparation, characterization and testing, as well as delivery and after-sales service, to ensure that we provide clients with all-round, one-stop service.

Applications

• N-Acetyllactosamine-QD nanoparticles can be used as biomarkers for cellular imaging and disease diagnosis.
• N-Acetyllactosamine-QD nanoparticles can be used as fluorescent probes to study the interactions of N-acetyl lactosamine and lectins.
• N-Acetyllactosamine-QD nanoparticles can be used as an efficient fluorescent probe to assess the carbohydrate-protein interactions.

Advantages of Us

• The synthetic method we use achieves glycosylation, azide reduction, and amine acetylation in one pot and does not require purification.
• NMR provides more structural information and does not destroy sugar QDs.
• Our team members have rich experience in glycobiology and nanomaterials research, and the synthesis process is highly efficient and stable, ensuring reliable product quality.

Publication Data

Frequently Asked Questions

• What are the unique features of N-acetyllactamide-QD nanoparticles?
  Our N-acetyllactamide-QD nanoparticles have excellent biocompatibility and targeting properties and are capable of accurately recognizing and binding to specific biomolecules, providing strong support for biomedical research and applications.
• What quantum effects do QDs have?
  QDs are nanoscale inorganic fluorescent dyes. It has some quantum effect properties such as surface effect, quantum size, dielectric confinement, macroscopic quantum tunneling effect, etc.

Using advanced synthesis techniques, CD BioGlyco rapidly and stably prepares high-quality N-acetyllactamide-modified QD nanoparticles. Depending on the client's needs, we offer personalized N-acetyl lactamine modification solutions to ensure specific biocompatibility and targeting of the QD nanoparticles. Feel free to contact us for customized synthesis solutions.