Properties
Description
Naftopidil 2HCl, soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets α1-adrenergic receptor, and 5-HT1A.
Molecular Formula
C24H28N2O3·2HCl
Targets
α1-Adrenergic receptor: 0.2 μM; 5-HT1A: 0.1 μM
Solubility
DMSO: 35 mg/mL (75.2 mM); Water: insoluble; Ethanol: 2 mg/mL (4.29 mM)
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Naftopidil 2HCl can be used to alleviate bothersome symptoms of BPH.
Storage
Store at -20℃, and keep desiccated.
