Properties
Description
Naftopidil 2HCl, soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets α1-adrenergic receptor, and 5-HT1A.
Molecular Formula
C24H28N2O3·2HCl
Targets
α1-Adrenergic receptor: 0.2 μM; 5-HT1A: 0.1 μM
Solubility
DMSO: 35 mg/mL (75.2 mM); Water: insoluble; Ethanol: 2 mg/mL (4.29 mM)
Applications
Naftopidil 2HCl can be used to alleviate bothersome symptoms of BPH.