Properties
Description
Nebivolol HCl, soluble in DMSO and insoluble in water and ethanol, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets β1-adrenoceptor.
Molecular Formula
C22H25F2NO4·HCl
Targets
β1-Adrenoceptor: 0.8 nM
Solubility
DMSO: 81 mg/mL (183.3 mM); Water: insoluble; Ethanol: insoluble
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Nebivolol HCl can be used for its arenoprotective effects.
Storage
Store at -20℃, and keep desiccated.
