Properties
Description
MLN4924, soluble in DMSO and ethanol and insoluble in water, interferes with the activation of the NEDD8-activating enzyme, potentially disrupting processes like protein degradation in cancer cells.
Molecular Formula
C21H25N5O4S
Solubility
DMSO: 78 mg/mL (175.86 mM); Water: Insoluble; Ethanol: 78 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
MLN4924 is studied to inhibit NAE, a critical part of the ubiquitin-proteasome pathway, crucial for cancer therapy research.
