NEDD8-activating enzyme (NAE) inhibitor TAS4464, Purity ≥98%

Synonym: 1848959-10-3; NEDD8-activating enzyme (NAE) inhibitor; TAS4464; TAS-4464; TAS 4464

CAS Number: 1848959-10-3
Compound CID: 124121703

Product Size

5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

TAS4464, soluble in DMSO and insoluble in ethanol and water, interferes with the activation of the NEDD8-activating enzyme, potentially disrupting processes like protein degradation in cancer cells.

Molecular Weight

506.5

Molecular Formula

C₂₁H₂₃FN₆O₆S

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 90 mg/mL (177.68 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

TAS4464 is used to inhibit NAE, affecting protein degradation pathways, investigated for cancer therapeutics.