Properties
Description
ZM223 interferes with the activation of the NEDD8-activating enzyme, potentially disrupting processes like protein degradation in cancer cells.
Molecular Formula
C23H17F3N4O2S2
Identity
Confirmed by NMR/HPLC/MS.
Applications
ZM223 is studied to inhibit NAE, crucial for protein degradation through the ubiquitin-proteasome system, with implications in cancer therapy.